治疗妊娠期较低的RA病活动
(健康日) - 根据在线发表于2月10日在线发表的一项研究,疾病活动和缓解性关节炎(RA)在怀孕期间患有现代治疗方法的妇女的可行性目标风湿病的血清。
Hieronymus T. W. Smeele, from the Erasmus Medical Center in Rotterdam, Netherlands, and colleagues assessed the feasibility of a modern treatment approach, including treat-to-target and the prescription of tumor necrosis factor (TNF) inhibitors, in patients with RA with a wish to conceive or who are pregnant. Disease activity was compared between the Preconception Counseling in Active RA (PreCARA; 309 patients; 2011 to present) cohort and the Pregnancy-induced Amelioration of Rheumatoid Arthritis (PARA; 253 patients; 2002 to 2010) cohort.
研究人员报告称,在Precara研究中,188名儿童出生,47.3%的女性在怀孕期间随时使用TNF抑制剂。在Precara队列中,平均疾病活性低于参考群组。在Precara队列中,75.4%的妇女在怀孕前患者低疾病活动或缓解,其在三个月的妊娠前增加至90.4%,而分别在比赛中分别为33.2和47.3%。队列。
“在患有RA的患者中,希望怀孕或怀孕,临床医生应该争取缓解或低疾病活动“作者写道。
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