图1所示。实验设置三种不同的模型。(一)海马切片实验。海马切片的示意图显示位置的电场刺激电极(敌人)在CA3区,和全细胞胞内记录电极(Rec)在CA1区。飞秒脉冲(激光)是通过使用2-Photon显微镜应用。扩大CA1的示意图显示位置的树突(红色)和脂质体(紫色)与连续激光扫描线(破折号),形成一个网格模式树突区域。例子cryo-transmission电子显微镜图像显示脂质体与空心黄金nanoshells(黑色;规模酒吧= 50海里)。(B)内嗅皮层楔实验。示意图显示的位置内嗅皮层楔,楔定位在两舱制油室的差距。 Liposomes were stimulated with ultrasound as they passed into the tissue chamber. Gray arrows indicate flow of ACSF. (C). In vivo preparation. Field potential signals were obtained via an extracellular recording electrode (Rec) in the left frontal cortex. Liposomes were stimulated using an ultrasound transducer coupled to an acoustic collimator and positioned on the dura above the cortex. Credit:制药学(2022)。DOI: 10.3390 / pharmaceutics14020468