H7N9流感男性患者睾酮水平与细胞因子/趋化因子水平的相关性a-g在感染H7N9禽流感的男性中观察到睾丸激素和细胞因子/趋化因子水平的回归。将H7N9男性血清中自然对数转化(Ln)睾酮表达水平与Ln转化细胞因子/趋化因子水平进行对比。睾丸素与细胞因子IL-6(白细胞介素6;a), IL-10(白细胞介素10;b), IL-15(白细胞介素15;c), IL-1RA(白介素1受体拮抗剂;d)和IL-1α(白细胞介素1α;e)从无死亡与幸存者相互作用的H7N9年轻男性中观察到的(18-49岁存活/死亡:n = 18/15);f, g观察到睾酮与细胞因子IL-6(白细胞介素6; f) and IL-10 (interleukin 10; g) in H7N9 older males without interaction between deaths and survivors (≥50 yrs survival/death: n = 27/11). a–g The best-fit line with 95% confidence intervals of the overall regression is shown in each figure. The center of the error distribution is the regression line. Two-tailed linear regression was performed. Adjustment for multiple hypotheses was not necessary due to the explorative nature of the study. A hollow blue circle represents survival, and a solid blue circle represents death. R squared values are shown in the figures. Credit:自然通讯(2022)。DOI: 10.1038 / s41467 - 022 - 34500 - 5