Elderly people can improve episodic memory via neurostimulation of the cerebellum, shows study

A recent study demonstrated that non-invasive stimulation of the right cerebellum led to improvements in episodic memory performance in healthy elderly individuals, at the end of a 12-day neurostimulation program, and also at the point of a 4-month follow-up.

The steady increase in average life expectancy poses significant challenges to individuals, families, and societies across multiple dimensions. Estimating that by 2050 one in every six individuals will be over the age of 65, the study of aging and its association withcognitive decline,neurodegenerative diseasesand overall frailty is becoming increasingly important.

Therefore, it has been an important goals of neurosciences research to understand the relationship between theaging brainandepisodic memorydeficits and to develop interventions to mitigate theage-related declinein our ability to remember personal past events (episodic memory).

The research team led by Jorge Almeida (Faculty of Psychology and Educational Sciences, University of Coimbra) published the article "The cerebellum is causally involved in episodic memory under aging," inGeroScience, which demonstrated that the cerebellum is one of the neuronal regions causally involved in episodic memory during aging.

If in the past the cerebellum was considered exclusively as the basis of motor coordination, controlling, for example, our balance and posture, in recent decades studies have proven that this brain region, located at the back of the brain, also decisively influences cognitive and emotional processes.

In this study, the team of researchers from universities of Portugal, Brazil, the U.S., and Iran delivered a 12-day neurostimulation program to the right cerebellum of 56 healthy elderly individuals aged 60 years old or over, and registered improvements in their episodic memory performance that lasted at least four months beyond the stimulation period.

The results demonstrate the causal relevance of thecerebellumin processes associated with long-term episodic memory, highlighting its role in regulating and maintaining cognitive processing.

According to Jorge Almeida, this work "opens up the possibility of developing non-pharmacological interventions to ameliorate typical age-related cognitive frailty that induce long-lasting improvements that, at least, outlast the four months tested herein."