%PDF-1.7 % 17 0 obj << /Type /Page /Parent 1 0 R /LastModified (D:20210524155419-04'00') /Resources 2 0 R /MediaBox [0.000000 0.000000 595.276000 841.890000] /CropBox [0.000000 0.000000 595.276000 841.890000] /BleedBox [0.000000 0.000000 595.276000 841.890000] /TrimBox [0.000000 0.000000 595.276000 841.890000] /ArtBox [0.000000 0.000000 595.276000 841.890000] /Contents 18 0 R /Rotate 0 /Group << /Type /Group /S /Transparency /CS /DeviceRGB >> /Annots [ 7 0 R 8 0 R 9 0 R ] /PZ 1 >> endobj 18 0 obj <> stream x\r8}Wt%3U x{LL噝[;<@$$!&  (? %ږ]8r,"F79h7޽?%UA3xyzďA$I E}SGO^)ꓷړBW9[r?9H=OGIAd1$b;-OC+7L|N[%S2':c5.peָJi`laFyI=kƢfI:IN8qbSQkx}kJVUѪ]t oRȖɯ9WG`pYI8yF ǫNS taJRGu*Mn #/"nmGfо"GP_'$Ndx:@ҹH_n awGK9]~CCǎ' Kp/Jnd~LL8 |hYnHZ( |l֢̂CTI;$MdG ^1kִtΚbK;mS+&#'5ղCӠCmkWaM+x]EU 'l#0e=\MGga[F"G7FM"/]&=(4lhbǬo5XtX-x䥖޷-\pQB$zk!Ԓ⟭*q_}qB?y&B$VDN]mؼ_'S4"`vg(IssV)´Ev0PBVENXUC=_xQD!1E;٪Z}KT"׌߁o鷆RKq6WZ08֠,zԚ-aR`k Y3g!~2ntM 7ôƣ:U+r:k1N&V#jF+SAus*bh2M^[j L8[!8NOH/]5oR#"E~$M(k0˘?WzPDeMD]*mK71 vg(,Ǝd+Dc9CL-JJ P vP R˰c]Iv.Ҕ%x ]9D^뮨Miا%Nfb3ej%SL u;9t[,(5鑼bY aBҮYѪhB5kB;QyNeiwxXԘz-}$&/Q:Tg+̦[Fo\n$QO+ :#:M,hU.e\Tv|KLb̖JxVUС"H}F}~^2^8%ܜ/uswX x Lv(t!Brv|:5-f#B(yf:ۢnv Zm0G֍ &zO|loqy 't\&@C_xtyC;INF+Ç>K}sM"bijP"%~符FtVgWm]n4~n=l18ZaaZ^ԂZGfÏr׎Q N)w]ɭٚrH PaZpC{1\WLUHF_qtz簽܇A"EYֽMkH6.lZdӒ9dͬ>>(S+ t3ni3-> /Annots [ 10 0 R 11 0 R 12 0 R 13 0 R 14 0 R 15 0 R 16 0 R ] /PZ 1 >> endobj 20 0 obj <> stream xZr۶}Wifl''tV4}HHDC*ZQy6JkR'iiGI&k#|" ?"Krx38}Cȿ`̎/ WOL?n]{s /3ٛ<|9~^YQG=wLbM kQxZ F+P hIcO+g_'+x;:Zc$JV-MUՠB Tu받pdGS7Bid ^"z$MG ཬ{w|)HEel]gs} : Sc9Ysia m.o<%ft4s",#8ÞXq,JTܶd6AQ_ ޯcYJh5N 1(KzŶ<48?ƾ?m {WCLxxUMXlu_$iԻ\q;cT%E2Z Z5ҡ<hĻGGxćW EXOJn1 ]jRNlءޠRy}:bEYʱ_@9h7(``D_?t kÎ{1aPs< b rP'Xt^96'y鏥1a\rǡF/|25}z'qخ:ҼzρřNXgQ"SKuMUTc4 y6 sQ&"s\&Yc>GVڥ돕F](%a0s^]B琢C&oiVJ,JB2X'U<(=yۺ[;Mr@+IԄ$OC1@OcLĎ,cB6Z. @ieYJ W9ˌ?c%IM`١8Þ ^#gT3t$iжK>{sjldZ.cEzB#筀Fpmae; ]Kcx)zz3U~("JHOp{! u,aUmHCah]OOY=d%N{6nOdQ-YNYNrr)WoS#TAB٧P)uoXA{[.] Ճa)oWTuN1I-mq=I(`nY#QT5t0UTi`.XV^\~Dvnm|@AϷSN,\j=PӔj]LAY ]ZBZJNmĵ{nԎ.E-|X*g=<)Rr3IZcZ|o_b]ZVzA^{U1Co-e3;pAwvoSW")ˡbβ4u[d?ӥD|QDҨ,vW’ z endstream endobj 1 0 obj << /Type /Pages /Kids [ 17 0 R 19 0 R ] /Count 2 >> endobj 3 0 obj <> endobj 5 0 obj <> endobj 6 0 obj <> endobj 21 0 obj <> stream JFIFHHExifMM* z(1>?QQ Q HHPaint.NET v3.5.10z%u0`:oCC." }!1AQa"q2#BR$3br %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz w!1AQaq"2B #3Rbr $4%&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz ?(f 1T$`9Sw(B@;~(]Cd꾫Es:aݻd2\(2F][&]ۢϲ|W͵L@A A 8 (CĝCglZE/ |Ezє{ xQʒ@[ྊ\/I4R0?6.7`ŴwPu|3/Z@Ogi}cFdFKoj?~8|p_A<ĺOkGPK $wRmkmF;YVx&rLj#p ׭axf|s$Ӿc:Qwm]N)Cψ[eYba98xB+oTÚwcRþ$U[ ?qΙ{&jv6Xo$=ԗ&7zgAxIִ.$3,mwc{+%g[!U@&Fϻm/#hci'7n[%It.&/ֶ+Zl~:wi~D>$}o+}@.[/+B6mnt8bi{zc.~F{eUe86g3 VT&> BK VؘXzSMesoM_&ϔIÍK?+hڿnt_ K]H '̽yrWA=O+|"!gɤItXe>Xs hwwG Eouqa /ş_~~'x} ]_^]/ 蚼:<cu/ h&omEۯicǪ\[,k}_uS}㏆W]G^tmf`Ks ]=va&h9n忔>75NWQτ0of,E (˰8hBC_ Jq'W UQKz,N>+`S%}b5ISJ]+(&QVN>eoy7xG4[]]3K{i$I>g-(mbynLIC,"*3f?-%`lfPx涽X"H'h"ֈ(TfeU:܉,a,R*I4xcxalOhGр|ia$cg,{gAHEu->]F,{-.,EX"I$XQD/3R.{{T&ҭ%4[OPnx"HhM :e}-Լ'=s:\iZ<+Lj5+1AɮLZx-☽G3 1I"kuχ+A}5'NxI8 gJk[oenm!x,=n=>}kjPx~M񧍼5k45a,RLiȖTFQMR&K;}r+XkY[y>2F=2~6>Gmi++<[WF76MH4>;;Kf۽ъM3ZE}c㿈*- -.|G5uI![ YR$$A>Eyׇ|7u;n>4׭JϷR[h!rVr\{~Ϛ >0jMg?_y_ Do/x;ÚƏi a𶕦f|Eqgk4V^RY]}F,/J%ՌAud%:x3Hg_4[+^ ҴKaXF'n.]Z(i$bef5GO:u]/a~.3N4xiG*a8ާ-U){G nJEڿ[m7wv5MYp|'gm # #%B?|鿲w­{+_|Q#VkxcZޛ{I]Wyak}..i˨iY9QwOA~hf{+ |Y;cڴ27G>|H,na8o; CEO,ZLP?SHK} e92W7/1aj¤aڄq4 қS7,5]%EƔc/uҒw\r/EnT y>!V+VK4X^Y{;+Ӫ=MqslEn?Zz'Ë}^2xĺGf70/M~*DU=坍G{wwvci%vZ$GY&J9dkՀ\6hs.F*ĩ"+S%s*{ qqDj3$ q^T24,Cn +=j񟍼q5k'\%ݎ{ͦuyq4X$y<ك2Ey%™|Icw]3#R[`{KցY [1*kLOdw ^OAkЏb<¿ <=6x0ׄ>(=*[ t]9-?IZ@}/>FۃQ@ endstream endobj 22 0 obj <> stream JFIFHHC     C   T"   1Ob"sb!Xm?F9e+ȵ7N;l 9mWMGfvRtUKUªLCmEdpǓUe_vY_TxSJsJ◧w\u_yΡ*9yX?yaMke+nH%0-DM7SŬi\RW<'͕~1YNVedŜxio=AOͮޙA>xk$AF$拕>h($<e*6 5&4@PfFǟ++++++*=7}kx3s8V|'-B 0ꛌD{V~tv`V6[k򜪸#mR2I\8 d+Yo&*iu~P6OkpH"fXlI،m߳ #a].>hFO U6-;&䛁pa+LL ir}< =er[h2d媞5N-lMLWm-t088ZtY]VE>]w2euƯ2լX zP$3 7a!k0b'f^pCdܛ!In.fr+0b]H L,V`C) Q!"1A02BRa?*z f>'/OL*b@{MVNC/Pq1@-L|f,M-*WCk0!+u4#M6ϩ>!0 F"zU*> uVpFFd2Mg_? 1A!Qaq"S #23Rb0BDr?Ɉq|ĹM%~bm,q.chaLXNrTxe{=3Py#Zoࡓ꬈8rF!!0xCD72(P,f+̺7/= D: BdF=$oނF=$oނF=$&Ҁ"<-NNC҆Ky8/& ڋp5$mqs0԰ϝMLHdj`ƸSRqKvE&)f@~\C[*Ա^1iyiKʶĪ#b%Z',ny?@[Sn5..I6$ϗ%fXrTkUxbn\QiUE\(El5]P%|MYA5{ryyqU+W#pN NWLHhω`SVtC24rAmQ_s93~pd{>^2. [Qg#2 mA2tq5w]=G2CɁU^axX=JsԬ $[Rhb0/y ! 4:Z(.x4BٯfeSo壹/= EfէV$M%m& B͸iY(U+JLVk+lY}K'̐Rr!e p~.+%dS?zp*yx[;0+Ƹj&3|,s97?(~͛y U&ET_20Vw璌U2bs$E+]l|?O͟6DiC Qr'Yۃ.BIEEji'\&*=͏DoT6=SB&Z_x:`&&K_T)-gN,׎5ЀmFៃDO(czǢ7{ީlz!feekyiCcˌm`DG2'*!1AQa q0@P?!fqK߾ )$7I $9,Y6Tҧ(%Ad1KF3fDٳAȉ_"^3]OUu]OUu]OUuMo|F?vs'5-w{\ xx90_}yPJIa:1mg*gћh^%)TcΞʆuلys!}}͜*&ܱ 00!^2M ւI)!jK73tIEl#Gx7N,ӬH'!K_"h5LKD TL#(%Y( 2%9P׷+drG;ZiyFB̚oמA[ Lf PrQIt$jVŖ :5ʑo; Ǐ+`o} lF1-hBLXpb$L[ʫ q"T=mՌ.} !c&};Q0~s"X \0dNs!x>l0&Ӯ;ޓf#{CzpCpgXްPcZTS2yq&"Hf8"}L7'f4vܢ.^&&Cw]_nQ^ kE%'AU>B2;=D.e\Yބ֨]hbB cBkFb;ocP.މRAd-2#ܷ|~BQ4ӕ\r-<0|WKbDg֓F H Bب 2Κ0` # 8Hq_700?Gp) JJZ s"!]S/R5Ov=Of^ c2,T̈́']{~?B0ЧLc6@0c2_e R;btPR,<Dᠾ)xr{?š~766[ϨҀ⦃^>4{ Y)_AcZA[t6(n@vdU%'!1A Qaq0@P?dCzAO7 0a] Kt a1]3@p3E@<C[P^ ; P(uzxjzBγԯ^nݻv:Yd0(f>1mxJL=AV*NVŠD'ʖ M-H"j /'( JPi`(5t}i /Z_}kTQ^P0+.]cYݴ…<ș VzʤLZjP!vx$7饩@BDp}+clT YD$֬ƹ'dj㓯Q`hpXYo Q"$ OfR t> ,{1V jb7.R-i g6p?e\iv !:SlM =9=Ѡ `QB=p?WM4HF @(:.%c", ` C % e?@J [P)<3,Zu:jAEb"y(( TU}Oc">+ H 8tG endstream endobj 4 0 obj << /Type /XObject /Subtype /Form /FormType 1 /Filter /FlateDecode /BBox [0.000000 0.000000 595.276000 76.535433] /Matrix [1 0 0 1 0 0] /Resources << /ProcSet [/PDF /Text /ImageB /ImageC /ImageI] /Font << /F2 5 0 R /F1 3 0 R >> /XObject << /I0 21 0 R >> >> /Length 197 >> stream xKkBA WeI&ڊU/ nʥBf8A3!(X4`JQj*Aj͕197f hkL[=µrw]F D%x2WC0 9)Z ^Wh}29yyu?4g=bT1߻a endstream endobj 2 0 obj << /ProcSet [/PDF /Text /ImageB /ImageC /ImageI] /Font << /F1 3 0 R /F2 5 0 R /F3 6 0 R >> /XObject << /XT4 4 0 R /I0 21 0 R /I1 22 0 R >> >> endobj 7 0 obj <> /H /I>> endobj 8 0 obj <> /H /I>> endobj 9 0 obj <> /H /I>> endobj 10 0 obj <> /H /I>> endobj 11 0 obj <> /H /I>> endobj 12 0 obj <> /H /I>> endobj 13 0 obj <> /H /I>> endobj 14 0 obj <> /H /I>> endobj 15 0 obj <> /H /I>> endobj 16 0 obj <> /H /I>> endobj 23 0 obj << /Title (FDA to investigate diabetes drug saxagliptin for possible heart failure risk) /Subject (FDA to investigate diabetes drug saxagliptin for possible heart failure risk) /Creator (Science X Network) /Producer (TCPDF 6.3.5 \(http://www.tcpdf.org\)) /CreationDate (D:20210524155419-04'00') /ModDate (D:20210524155419-04'00') /Trapped /False >> endobj 24 0 obj << /Type /Metadata /Subtype /XML /Length 4809 >> stream application/pdf FDA to investigate diabetes drug saxagliptin for possible heart failure risk FDA to investigate diabetes drug saxagliptin for possible heart failure risk 2021-05-24T15:54:19-04:00 Science X Network 2021-05-24T15:54:19-04:00 2021-05-24T15:54:19-04:00 TCPDF 6.3.5 (http://www.tcpdf.org) uuid:4bc846ab-dfd5-1d47-dbd0-b46f5911d626 uuid:4bc846ab-dfd5-1d47-dbd0-b46f5911d626 http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal Adobe PDF Schema InstanceID URI http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text endstream endobj 25 0 obj << /Type /Catalog /Version /1.7 /Pages 1 0 R /Names << >> /ViewerPreferences << /Direction /L2R >> /PageLayout /SinglePage /PageMode /UseNone /OpenAction [17 0 R /FitH null] /Metadata 24 0 R >> endobj xref 0 26 0000000000 65535 f 0000005963 00000 n 0000018736 00000 n 0000006030 00000 n 0000018235 00000 n 0000006136 00000 n 0000006247 00000 n 0000018893 00000 n 0000019141 00000 n 0000019392 00000 n 0000019641 00000 n 0000019895 00000 n 0000020140 00000 n 0000020420 00000 n 0000020650 00000 n 0000020934 00000 n 0000021216 00000 n 0000000015 00000 n 0000000497 00000 n 0000003480 00000 n 0000003993 00000 n 0000006361 00000 n 0000011997 00000 n 0000021434 00000 n 0000022010 00000 n 0000026902 00000 n trailer << /Size 26 /Root 25 0 R /Info 23 0 R /ID [ <4bc846abdfd51d47dbd0b46f5911d626> <4bc846abdfd51d47dbd0b46f5911d626> ] >> startxref 27112 %%EOF